Polysaccharide in Ganoderma lucidum has a broad-spectrum inhibitory effect on tumors and is a good adjuvant for clinical treatment of tumors. Experiments show that Ganoderma lucidum polysaccharide has a significant inhibitory effect on liver cancer caused by aflatoxin. Ganoderma lucidum polysaccharides can also activate macrophages to enhance the ability of macrophages to phagocytosis. There are also experiments showing that Ganoderma lucidum anticancer mainly acts by inhibiting the synthesis of cancer DNA.
Different parts and extracts of Ganoderma lucidum have different effects on blood sugar. It increases the concentration of plasma insulin and accelerates the metabolism of glucose. It not only increases the utilization of sugar by surrounding tissues but also enhances the utilization of glucose by the liver by enhancing the activity of various key enzymes involved in liver glucose metabolism.
3. Liver protection
Pharmacological tests showed that Ganoderma lucidum spore powder had a protective effect on D-galactosamine-induced liver pathological model in mice. Ganoderma lucidum can lower blood fat, reduce liver index, reduce liver steatosis, and prevent liver damage caused by carbon tetrachloride and prevent its fatty degeneration.
The immunomodulatory effects of Ganoderma lucidum and its polysaccharides can promote the anabolism of nucleic acid proteins, the activity of anti-oxidative free radicals and the ability to prolong the divisional algebra of metabolized cells in vitro, suggesting the anti-aging mechanism of Ganoderma lucidum. In addition, Ganoderma lucidum polysaccharide can promote the DNA activity of T lymphocytes deoxyribonucleic acid DNA in mice, and promote cell DNA synthesis, which is also one of its anti-aging mechanisms.
6. Anti-inflammatory analgesia
Ganoderma lucidum polysaccharide can significantly inhibit the non-specific inflammation of mice caused by croton oil, smoke, and Escherichia coli endotoxin, and prolong the survival time of mice with hypoxemia caused by sodium nitrite and cardiotoxic mice. To improve the survival rate of mice with acute pulmonary edema induced by adrenaline, the mechanism may be related to the inhibition of seizure of leukocytes in some tissues, and its characteristics are similar to those of non-steroidal anti-inflammatory drugs. Some British scholars used the acetic acid writhing method to confirm that the methylene chloride extract of Ganoderma lucidum showed obvious analgesic effect, and the inhibition rate was 35.6%.
7. Protect the heart
Ganoderma lucidum has a comprehensive protective effect on the heart, which can improve myocardial blood oxygen supply and enhance myocardial contractility in various animals. In addition, it can dilate the coronary artery, counteract the vasoconstriction response of pituitrin, and increase the myocardial ATP content in rats. The role of reducing the energy consumption of animal myocardial energy.
Ganoderma lucidum polysaccharide can significantly prolong the clotting time of mice, significantly prolong the thrombus formation time in mice, inhibit the formation of thrombus in blood stasis rats, and reduce the plasma specific viscosity of blood stasis rats. The experiment proves that Ganoderma lucidum is a strong inhibitor of platelet aggregation, which can be used to prevent arterial thrombosis and prevent the occurrence and development of cardiovascular and cerebrovascular diseases caused by increased platelet activity.
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