Nattokinase (NK) is a subtilisin that is a kinds of serine protease produced by natto bacillus subtilis during the fermentation of natto. Nattokinase have a good effect on dissolving blood clots, reducing blood viscosity, improving blood circulation, softening and increasing vascular elasticity.
A significant function of nattokinase is the role of thrombolysis. After oral administration of nattokinase in healthy people, the following effects occur:
① Nattokinase can significantly shorten the dissolution time of special globulin (ELT);
② Nattokinase can increased fibrinolytic activity in plasma.
③ Nattokinase can increased T-PA volume in plasma. Due to the safety, stability and good thrombolysis of NK, it may be used as an oral agent for thrombosis.
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